Fig. 5From: Intracranial emergencies in neurosurgical oncology: pathophysiology and clinical managementCerebral autoregulation. Initial changes in CPP are associated with maintenance of CBF due to appropriate changes in arteriolar resistance. More marked changes in CPP are eventually associated with loss of autoregulation, leading to a reduction (with hypotension) or an elevation (with marked hypertension) in CBFBack to article page